L43.0
Conditions
Interventions
Group 1: Treatment of the OLP lesion with Er:YAG
Group 2: Treatment of the OLP lesion with Nd:YAG
Group 3: Treatment of the OLP lesion with combination of Er:YAG + Nd:YAG
Sponsors
Universitätsklinikum TübingenPoliklinik für Zahnärztliche Prothetik
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria for the present study were the OLP lesions refractory to conservative therapy, which was stated after the signs of OLP did not disappear within the last 6 months.
Exclusion criteria
Exclusion criteria: The exclusion criteria were any malignance signs (n =5), presence of HIV, HBV, HSV, EBV, CMV (n = 15) and exacerbation of hypertonia and diabetes mellitus (n = 12), allergic reactions on the received conservative therapy (n = 2), pregnant female patients, or those either going to be pregnant or being in lactation period (n = 1).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficacy of each treatment method was assessed basing on the inflamatory cytokines, pain and odem level reduction. Based on this criteria, the Er:YAG laser type demonstrated the superior treatment outcome, followed by the combination of Er:YAG + Nd:YAG and Nd:YAG solely. | — |
Secondary
| Measure | Time frame |
|---|---|
| The significant cytokine level reduction was demonstrated on the 14th and 30th day, using each type of laser, which means that the chosen inflamatory cytokines (IFNy, IL1b, IL6) are suitable for the lase effectiveness analysis. | — |
Countries
Russia
Contacts
Public ContactAlexey Unkovskiy
Universitätsklinikum TübingenPoliklinik für Zahnärztliche Prothetik
Outcome results
None listed