Healthy subjects
Conditions
Interventions
Group 1: Subjects in Arm 1 will receive a 75g-glucose solution as a test product containing a different kind and amount of fibre during every intervention visit. During the control visit a pure 75g-gl
Sponsors
Technische Universität München Lehrstuhl für Ernährungsmedizin
Eligibility
Sex/Gender
All
Age
35 Years to 67 Years
Inclusion criteria
Inclusion criteria: - Providing written informed consent - 35-67 years old - Waist circumference >88 cm (women) and >102 cm (men)
Exclusion criteria
Exclusion criteria: - Not providing written informed consent, - Parallel participation in another interventional study - Chronic diseases: Diabetes mellitus, untreated hypertension (>160/95 mmHg), untreated hormonal diseases (e.g. hyperthyroidism, hypothyroidism), chronic liver diseases (e.g. HBV, HCV), autoimmune diseases (rheumatism, ulcerative colitis, Crohn's disease), chronic infections (e.g. HIV), cardiovascular disease, tumor disease, diverticulosis, - Acute infectious diseases, - Allergy or sensitivity to the study products, - Current dietary fibre supplementation - Pregnancy and breastfeeding, - Having donated blood in the prior 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes of the study are following blood-glucose related parameters: - peak glucose value - time to peak - glucose AUC - shape of the glucose curve. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes are: - peak insulin value - insulin AUC - results of the 13C-breath test (for the indirect assessment of the gastric emptying) | — |
Countries
Germany
Contacts
Public ContactKatarzyna Pietrynik
Technische Universität München Lehrstuhl für Ernährungsmedizin
Outcome results
None listed