F42.2
Conditions
Interventions
Group 1: Interventional = Exposure therapy in mixed reality (MR) for the treatment of washing compulsions
Group 2: Control group = Participation in self-guided exposures
Sponsors
Hamburgische Investitions- und Förderbank (IFB); Europäischer Fonds für regionale Entwicklung (EFRE)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - presence of OCD with washing compulsions (M.I.N.I. diagnosis) - the desire for treatment - no inpatient treatment (other outpatient treatment offers may be continued) - Gender: Both, male and female - Minimum Age: 18 Years - Maximum Age: 80 Years - consent to participate in exposures in MR or self-guided exposures as well as the all three assessments (informed consent) - ability to provide consent - sufficient understanding of the German language
Exclusion criteria
Exclusion criteria: - lifetime schizophrenia (F.20) or bipolar disorder - acute suicidal tendencies - mania - severe neuropsychological disease - current substance dependence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Yale-Brown Obsessive Compulsive Scale (Y-BOCS): The Y-BOCS is regarded as gold-standard for the assessment of OCD symptoms and symptom severity during the last week (baseline-, post after 6 weeks and follow-up after 3 months). | — |
Secondary
| Measure | Time frame |
|---|---|
| Sudden Units of Distress (SUD): Self-reported assessment of distress (before, during and after the exposure; session 3–6). Obsessive Compulsive Inventory- Revised (OCI-R): The OCI-R is a self-rating questionnaire that assesses OCD symptom severity during the last month (baseline-, post after 6 weeks and follow-up after 3 months). Obsessive-Beliefs-Questionnaire (OBQ): The OBQ is a self-rating questionnaire that assesses OCD relevant dysfunctional beliefs (baseline-, post after 6 weeks and follow-up after 3 months). Generalized Anxiety Disorder 7 (GAD-7): The GAD-7 is a self-rating questionnaire for the assessment of anxiety symptoms, which can be used as a screening instrument to identify a generalized anxiety disorder (baseline-, post after 6 weeks and follow-up after 3 months). Brief Experiential Avoidance Scale: The BEAQ is a self-rating questionnaire and assesses experiential avoidance, which describes the unwillingness to remain in contact with distressing emotions (baseline-, post after 6 weeks and follow-up after 3 months). Beck Depression Inventory-II (BDI-II): The BDI is a self-rating questionnaire to measure depressive symptoms over the past two weeks (baseline-, post after 6 weeks and follow-up after 3 months). Beliefs Questionnaire (BQ): A self-assessment questionnaire to assess dysfunctional beliefs (baseline-, post after 6 weeks and follow-up after 3 months). Quality of Life - Global item (WHO-QOL-BREF): Global item of the self-assessment questionnaire that measures quality of life (baseline-, post after 6 weeks and follow-up after 3 months). Questionnaire on attitudes towards exposure in MR: The questionnaire captures the previous, subjective attitude of patients towards exposure in mixed reality (baseline). Temple Presence Inventory (TPI): The TPI is a self-rating questionnaire to assess the sense of presence in MR (post after 6 weeks). Questionnaire on simultaneous treatments: The questionnaire on simultaneous treatments assesses if and | — |
Countries
Germany
Contacts
Public ContactFranziska Miegel
Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Arbeitsgruppe Klinische Neuropsychologie
Outcome results
None listed