Automated recording of movement profiles of patients with Parkinson's syndromes

Conditions

G20

Vera Tschentscher, Judith Oppermann, Julius Welzel, Johanna Geritz, Ralf Gold et al. (10 authors)

Neurological Research and Practice2025-07-28

Clinical and device-based predictors of improved experience of activities of daily living after a multidisciplinary inpatient treatment for people with Parkinson's disease: a cohort study.

Oppermann J, Tschentscher V, Welzel J, Geritz J, Hansen C, Gold R, Maetzler W, Scherbaum R, Tönges L.

2024-09-233 citations

10.1177/17562864241277157

Parkinson’s disease multimodal complex treatment improves gait performance: an exploratory wearable digital device-supported study

Raphael Scherbaum, Andreas Moewius, Judith Oppermann, Johanna Geritz, Clint Hansen et al. (8 authors)

Journal of Neurology2022-07-2114 citations

10.1007/s00415-022-11257-x

Interventions

Group 1: The following values are determined for patients with idiopathic Parkinson's syndrome: - Determination of the stage in the modified scale according to Hoehn and Yahr and further motor and no

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Male and female patients with idiopathic Parkinson's syndrome according to UK Brain Bank criteria Further inclusion criteria: - Written informed consent based on Good Clinical Practice (GCP) and local legislation - Age of majority - Reconnaissance capability - Legal capacity

Exclusion criteria

Exclusion criteria: - Lack of agreement with protocol - Drugs or alcohol dependency within 6 months before signing the consent form - Stereotactic surgery in the history - Electroconvulsive therapy in the last 180 days before screening - Severe dementia based on a score of <10 in the Mini Mental State Examination (MMSE) - Depression with suicidal thoughts (previous episodes of severe depression are not a criterion for exclusion) - Illiteracy or insufficient language skills

Design outcomes

Primary

Measure	Time frame
Determination of the effectiveness of sensor-based parameters for the evaluation of treatment success in motor, gait and executive dysfunctions of Parkinson's patients. The questionnaires as well as the sensor measurements are collected at the beginning of the therapy, time T1, and at the end of the therapy, time T2.	—

Secondary

Measure	Time frame
- Determination of output values of sensor-based parameters for the evaluation of motor, gait and executive function disorders in Parkinson's patients - Determination of the reproducibility of sensor-based parameters for motor, gait and executive dysfunctions in patients, which is necessary for the calculation of the minimal detectable change and thus for the detection of an effective treatment - Exploratory comparison of the above parameters / changes in parameters during the course of treatment, with clinical and quantitative imaging parameters. The questionnaires as well as the sensor measurements are collected at the beginning of the therapy, time T1, and at the end of the therapy, time T2.	—

Measure

Time frame

- Determination of output values of sensor-based parameters for the evaluation of motor, gait and executive function disorders in Parkinson's patients - Determination of the reproducibility of sensor-based parameters for motor, gait and executive dysfunctions in patients, which is necessary for the calculation of the minimal detectable change and thus for the detection of an effective treatment - Exploratory comparison of the above parameters / changes in parameters during the course of treatment, with clinical and quantitative imaging parameters. The questionnaires as well as the sensor measurements are collected at the beginning of the therapy, time T1, and at the end of the therapy, time T2.

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Countries

Germany

Contacts

Public ContactVera Tschentscher

St. Josef-Hospital

vera.tschentscher@rub.de0234-5092475

Outcome results

None listed