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Management of pharyngeal residues in neurogenic dysphagia: Another clearing effect of capsaicin after cough stimulation with cayenne aersosol

Management of pharyngeal residues in neurogenic dysphagia: Another clearing effect of capsaicin after cough stimulation with cayenne aersosol

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00020893
Enrollment
40
Registered
2020-02-21
Start date
2020-03-04
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R13

Interventions

Group 1: Group A - first: irritation with capsaicin aerosol - afterwards (if necessary, if residuals still exist): mechanical stimulation with endoscope Group 2: Group B - First: mechanical stimulatio

Sponsors

Kliniken Valens
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Male and female persons with neurogenic dysphagia who receive a video endoscopic swallowing examination (FEES) in the Klinik Valens ? Age> 18 years ? Diagnoses: stroke (infra- or supratentorial), Parkinson's syndrome (idiopathic Parkinson's syndrome, multi-system atrophy, progressive supranuclear palsy, corticobasal degeneration, Lewy-body dementia), intracerebral hemorrhage, traumatic brain injury (without critical illness polyneuro- / -Myopathy) ? 1 out of 4 signs of dysphagia (rattling noises in the airways, moist voice sound at rest or after eating, coughing when taking solid and liquid food, recurrent respiratory infections) ? reflective cough after pharyngeal exposure with capsaicin-containing aerosol; Peak Cough Flow> 2.7 l / s (160 l / min) ? Patients who are unable to completely eliminate pharyngeal residuals using arbitrary clearing maneuvers (compensation strategies, night drinking, throat clearing, swallowing, reflex swallowing / coughing) or after reflex cough caused by food / liquid aspiration / penetration ? Written consent of the test subjects after the information has been given

Exclusion criteria

Exclusion criteria: Patients with structural dysphagia (e.g. trauma, tumor, radiation) • Complication-free, requirement-covering food and liquid intake • Patients with chronic respiratory diseases ? Patients with severe cardiovascular diseases including uncontrolled arterial hypertension ? reflective cough after pharyngeal exposure with capsaicin-containing aerosol; Peak cough flow <2.7 l / s (160 l / min) ? Diagnoses: Neuromuscular Diseases, Encephalomyelitis Disseminata, Critically Illness Polyneuro - / - Myopathy ? Patients without pharyngeal residuals • disturbed nose anatomy

Design outcomes

Primary

MeasureTime frame
It is being examined whether the patients can now, through the reflective cough, remove the pharyngeal residues by swallowing or spitting out or whether they can be obtained by the authorities, so that the risk of developing aspiration pneumonia can be improved.

Secondary

MeasureTime frame
If pharyngeal residues still exist after one of the cough stimulations mentioned has been used, a crossover is used for ethical reasons and the respective intervention is used in the other group.

Countries

Switzerland

Contacts

Public ContactEliane Lüthi-Müller

Kliniken Valens

eliane.luethi@kliniken-valens.chTel +41 (0)81 303 13 47

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026