T20-T32
Conditions
Interventions
Group 1: Patients who fulfil our inclusion criteria will be connected to an invasive blood pressure measuring system immediately as soon as they reach our hospital.
Upon arrival in the shock room of o
Sponsors
BG Klinikum Unfallkrankenhaus Berlin gGmbH (ukb)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • burn injury with total body surface area (TBSA) =20%, severity of 2nd - 4th degree • patient's age =18 years • initial treatmeant in general anesthesia with controlled ventilation
Exclusion criteria
Exclusion criteria: • relevant cardiac and/or vascular disease which would impede with accurate determination of pre- and afterload via pulse contour analysis (e.g. atrial fibrillation, heart failure, peripheral arterial disease, valvular disease) • spontaneous breathing • pregnancy • rejection of participation in the clinical trial by patient or guardian • TEN or Lyell- syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of fluid rescuscitation in total volume and distribution compared to calculated fluid rescuscitation with Parkland/ Baxter formula. | — |
Secondary
| Measure | Time frame |
|---|---|
| Organ failure, necessity of organ replacement therapy, mortality. Additionally, we plan to examine a possible correlation between initiallly measured pre- and afterload parameters and secondary outcomes. | — |
Countries
Germany
Contacts
Public ContactKonrad E. Liesenborghs
BG Klinikum Unfallkrankenhaus Berlin gGmbH (ukb)
Outcome results
None listed