Hemodynamic change and its outcome-relevant influence during transcatheter aortic valve implantation. I35.0
Conditions
Interventions
Group 1: Pre-operative neurocognitive testing
Pre-operative blood sampling at the onset of anesthesia
Recording of anesthesia data/hemodynamics
Post-operative blood sampling on 1st post-operative day
Sponsors
Immanuel Klinikum Bernau, Herzzentrum Brandenburg
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Elective transcatheter aortic valve implantation (TAVI). No contraindication to neurocognitive testing Ability to understand the scope and significance of the study Written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Emergency intervention Dialysis patients Patient (or proxy) is unable to provide written informed consent to participate in the give written informed consent for participation in the study Diseases, due to which neurocognitive testing is not possible Attending physician does not recommend participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AKI incidence in patients above versus below median cerebral saturation (rSO2). | — |
Secondary
| Measure | Time frame |
|---|---|
| - ? creatinine and ? NT-proBNP in patients* above versus below the median cerebral saturation (rSO2). - Cumulative cerebral desaturation (AUC, maximum, minimum). - Time [min] rSO2 <50% / frequency of episodes. - Time to MAD/rSO2 recovery (+/-10% from baseline) after RVP. - Changes in cognitive tests | — |
Countries
Germany
Contacts
Public ContactAnja Haase-Fielitz
Immanuel Klinikum Bernau Herzzentrum BrandenburgUniversitätsklinikum der Medizinischen Hochschule Brandenburg Theodor Fontane
Outcome results
None listed