E66 E78 K63
Conditions
Interventions
Group 1: On the first day of the study, subjects consume a standardized meal at around 7 p.m. and are asked to provide a stool sample. From this point on, subjects are asked not to consume any other w
8, blood samples are taken from the subjects. Subsequently, subjects will receive another standardized meal and will also be able to consume unrestricted food...
A sample is then also taken from the f
Sponsors
Technische Universität München, Wissenschaftszentrum Weihenstephan, Lehrstuhl für Molekulare Ernährungsmedizin
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Age 20 to 40 written consent Europeans BMI 18-35 kg/m² Women and Men (1:1)
Exclusion criteria
Exclusion criteria: Missing written consent active smokers chronic diseases like: chronic infection (e.g. HIV) diagnosed liver diseases (e.g. HBV,HCV) diagnosed diabetes mellitus required to undergo dialysis pregnant or breastfeeding women active participation in other interventionstudies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood: Analysis of lipid species and bile acids by mass spectrometry. Analysis of feces: Analysis of bacterial communities by 16S rRNA sequencing. Analysis of bile acids by mass spectrometry. Collection of clinical chemistry parameters relevant to lipid metabolism. By combining these data, we try to find a correlation between different microbiota species and blood lipid parameters and bile acids in relation to dietary cholesterol. | — |
Secondary
| Measure | Time frame |
|---|---|
| The generated Data are merged to find a correlation between microbiota and the cholesterol load as single aim, therefore a secondary outcome cannot be defined in this case. | — |
Countries
Germany
Contacts
Public ContactAkim Strohmeyer
Technische Universität München, Wissenschaftszentrum Weheinstephan, Lehrstuhl für Molekulare Ernährungsmedizin
Outcome results
None listed