K05.3 K05.2
Conditions
Interventions
Group 1: healthy control subjects
Group 2: Patients with diagnosed periodontitis receive MRI scan and clinical periodontitis-specific examination per patient - before treatment and 3 months after comp
Sponsors
Klinikum rechts der Isar, Abteilung für Diagnostische und Interventionelle Neuroradiologie, TU München
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Included were both, male and female patients with diagnosed, periodontitis as well as healthy control subjects (in the context of sequence optimization and as a healthy comparison collective). Diagnosis of generalized periodontitis was made when clinical periodontal attachment loss was present at >2 interdental sites at non-adjacent teeth and/or a probing pocket depth of >3mm at oral or lingual sites. At least 30% of teeth had to be affected by periodontitis. None of the healthy control subjects and the periodontitis patients received periodontal treatment within the past six month.
Exclusion criteria
Exclusion criteria: Patients with contraindications for an MRI examination (e.g. pacemaker, implanted defibrillator, artificial heart valves, cochlear implants, metal splinters, insulin pumps) were excluded. Further exclusion criteria were patients with pronounced claustrophobia, psychomotor agitation, pregnant as well as breastfeeding women and patients with a metastatic, malignant underlying disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Signal changes in MRI (signal-to-noise-ratio as well as volume of changes in mm3 - clinically determined parameters (bleeding on probing, pocket probing depth) | — |
Secondary
| Measure | Time frame |
|---|---|
| bone resorption, attachment loss | — |
Countries
Germany
Contacts
Public ContactMonika Probst
Klinikum rechts der Isar, Abteilung für diagnostische und interventionelle Neuroradiologie, TU München
Outcome results
None listed