end stage liver disease
Conditions
Interventions
Group 1: patients with biliary complications following liver transplantation and need for Intervention/surgery
Group 2: patients without biliary complications following liver transplantation
Sponsors
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie LMU, Klinikum der Universität München Campus Großhadern
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: patients >18 years patients able to give informed consent signed informed consent signed informed consent for biobanking end stage liver disease with need and organ availability for liver transplantation
Exclusion criteria
Exclusion criteria: patients < 18 years patients not able to give informed consent patients without liver Transplantation patients without informed consent for biobanking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes of the biliary microbiota follwing liver transplantation (diversity, UniFrac Analysis, principal coordinate Analysis) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of biliary microbiome of donor vs. recipient (OTUs, diversity, PCoA) Evaluation of conventional microbial swabs correlation of biliary and fecal and salivary microbiome to clinical data | — |
Countries
Germany
Contacts
Public ContactKoordinationszentrum Chirurgische Studien KCS
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie Klinikum der Universität München
Outcome results
None listed