Calprotectin for Evaluation of Acute Infection and Sepsis and Prognosis Characterization in the Emergency Department

Calprotectin for Evaluation of Acute Infection and Sepsis and Prognosis Characterization in the Emergency Department - CASCADE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00020521

Enrollment

384

Registered

2020-05-13

Start date

2020-05-18

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41 A49

Interventions

Group 1: Study type: Non interventional study, other studies The patient receives a treatment according to the usual care (Standard of Care). In addition, once 6ml blood are taken. These are used to

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients presenting or admitted to the emergency department with clinical signs of acute infection, as determined by the attending physician.

Exclusion criteria

Exclusion criteria: Age <18 years

Design outcomes

Primary

Measure	Time frame
Predictive power (positive and negative predictive power) of Calprotectin in relation to the presence of a bacterial, viral or no infection.	—

Secondary

Measure	Time frame
Predictive power (positive and negative predictive power) of Calprotectin in relation to: - 30 day mortality - requiring intensive care within 72hrs of admission - manifestation of organ failure - indicated antibiotic therapy	—

Countries

Germany

Contacts

Public ContactWolfgang Bauer

Studienzentrale der Zentralen Notaufnahme

Wolfgang.Bauer@Charite.de030450652897

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026