C18 C19 C20 C50 C61
Conditions
Interventions
Group 1: Individualized (at least 3 per week over 30 min) strength/endurance training by an online video presentation and 1 per week of outdoor training (depending on the patient, jogging, walking, c
Sponsors
University Leipzig, Institute of Sport Medicine & Prevention
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: - Patients according to TNM status (UICC 8th. Ed.) for tumor resection of the primary case (carcinomas ICD): C18/19/20 colorectal, C50 breast, C61 prostate. - T-stage: T1 to T3; N-stage: each N; M-stage: M0. In addition, patients with pre-surgical neoadjuvant pre-treatment as well as distant metastases (M1 stage) can be included in synchronous or metachronous RO resection (regarding primary tumor) and without intermediate chemotherapy. - Age between 18 and 75 years - ECOG congestion of 1 or better and without acute cardiac, renal, hepatic, endocrine, bone marrow or cerebral impairment
Exclusion criteria
Exclusion criteria: - Complications after tumor surgery, which prolong the convalescence and limit the physical activity relevant for the program - Presence of a second malignant tumour if therapy was less than 5 years ago - Contraindication for the sports programme: orthopaedic, rheumatological, cardiovascular or neurological diseases and muscular diseases - Any acute and active disease that prevents the termination of participation in the study - Active alcohol abuse and consumption of illegal drugs within the last 6 months before inclusion in the study - Lack of patient compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients in the IG have a 13% higher VO2max after 6 months of intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| - significant improvement in the results of tumour-specific accompanying measurements (liquid biopsy, CTC, cfDNA, ctDNA, microRNA) and tumour markers - significant reduction of hospitalizations by 15% in the IG compared to the KG - significant improvement of quality of life, fatique, depression (improvement of scores by 10%) - increase of the energy consumption by 500 kcal (or 500 met/min) per week in the IG compared to the KG - increase in patient compliance in the IG (95%) compared to the KG | — |
Countries
Germany
Contacts
Public ContactRoberto Falz
University Leipzig, Institute of Sport Medicine & Prevention
Outcome results
None listed