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Augmenting treatment for Major Depression with a Positivity-AAT-Training

Augmenting treatment for Major Depression with a Positivity-AAT-Training - Pos-AAT

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
DRKS
Registry ID
DRKS00020463
Enrollment
200
Registered
2020-04-14
Start date
2020-04-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32.0 F32.1 F32.2 F33.0 F33.1 F33.2 F34.1

Interventions

Group 1: Inpatients experiencing a depressive episode receive 6 sessions of a specific Approach-Avoidance-Task. Each training session lasts about 15 minutes. During the training, participants use a jo

Sponsors

Clinical PsychologyBehavioural Science InstituteRadboud University Nijmegen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Current diagnosis of a major depression according to the ICD-10, this will be the following diagnoses: F32.0 Mild depressive episode F32.1 Moderate depressive episode F32.2 Severe depressive episode without psychotic symptoms F33.0 Recurrent depressive disorder, current episode mild F33.1 Recurrent depressive disorder, current episode moderate F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms F34.1 Dysthymia (diagnosed by treating therapist or doctor); a score higher than 11 on Beck Depression Inventory II (BDI-II); sufficient German language skills.

Exclusion criteria

Exclusion criteria: Neurological disorder including epilepsy, diagnosed by a doctor; Acute suicidality (checked during admission); Diagnosis of a current substance dependency; Past or current psychotic episodes; Less than 8 years of school education.

Design outcomes

Primary

MeasureTime frame
Changes in scores on the Patient Health Questionnaire depression scale (PHQ-8), applied before the first training session and prior to the patients' discharge (i.e., after the entire training has been completed).

Secondary

MeasureTime frame
Manipulation check: Reaction times during the AAT, before the first and after the sixth training session. Generalisation: Number of key presses to change the duration of how long a picture is presented during the Motivated Viewing Task, before the first and after the sixth training session. Generalisation: Reaction times and number of key presses following trained and untrained positive pictures during the AAT and Motivated Viewing Task, before the first and after the sixth training session. Generalisation: Number of correctly unscrambeld negative sentences compared to the total number of correctly unscrambled sentences during the Scrambled Sentence Task (SST), before the first and after the sixth training session. Scores on the Dimensional Anhedonia Rating Scale (DARS), before the first training session and prior to discharge. Scores on the Snaith–Hamilton Pleasure Scale (SHAPS), before the first training session and prior to discharge. 12-months- follow-up: Scores on the Patient Health Questionnaire depression scale (PHQ-8). 12-months-follow-up: Assessment of working ability.

Countries

Germany

Contacts

Public ContactJohannes Lindenmeyer

Salus Klinik Lindow

lindenmeyer@salus-lindow.de033933 / 88-110

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026