G24.3
Conditions
Interventions
Group 1: Botulinum toxin injection + physiotherapy
Group 2: Botulinum toxin injection + cupping therapy
Sponsors
Neurologie Universitätsklinikum Jena
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - CD diagnosed classifiable with Col/Cap-classification (see also EC) - Continuously treated with BoNT-A (Abobotulinumtoxin A) in three months interval (aiming to prevent bias by using different BoNT-A-products with different dosing strategies) - At least 12 months treatment without relevant BoNT-A scheme changes over the last 3 injections
Exclusion criteria
Exclusion criteria: - CD with Antecollis/-caput only - CD without dystonic symptom (only tremor) - Contraindications for physiotherapy treatment - Contraindications for BoNT-A treatment - Refusal of study participation or simultaneous participation in other studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary object is the total Toronto Western Spasmodic Rating Scale (TWSTRS) score. Evaluation will be carried out at the start and 3, 6 and 9 months later. Primary Outcome will be evaluated 6 months after the individual start (after the intervention). | — |
Secondary
| Measure | Time frame |
|---|---|
| • TWSTRS severity, disability and pain scores • Static and mobility of the cervical spine which will be detected by an ultrasonic based measuring system (ZEBRIS) • SF-12 to evaluate the generic health and pain • CDQ-24 to evaluate disease-specific quality of life Measuring time points will be at the start and 3, 6 and 9 months later. | — |
Countries
Germany
Contacts
Public ContactAlbrecht Günther
Neurologie Universitätsklinikum Jena
Outcome results
None listed