Reduction of antibiotic resistance in uncomplicated urinary tract infections by treatment according to national guidelines in the ambulatory care

Conditions

N30.0 N30.9 N39.0

Angela Schuster, Paula Tigges, Julianna Grune, Judith Kraft, Alexandra Greser et al. (14 authors)

BMC Health Services Research2025-08-30

Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial

Guido Schmiemann, Alexandra Greser, Andy Maun, Jutta Bleidorn, Angela Schuster et al. (14 authors)

BMJ2023-11-0221 citations

10.1136/bmj-2023-076305

REDuction of Antibiotic RESistance (REDARES) in urinary tract infections using treatments according to national clinical guidelines: study protocol for a pragmatic randomized controlled trial with a multimodal intervention in primary care.

Gágyor I, Greser A, Heuschmann P, Rücker V, Maun A, Bleidorn J, Heintze C, Jede F, Eckmanns T, Klingeberg A, Mentzel A, Schmiemann G.

2021-09-237 citations

10.1186/s12879-021-06660-0

Interventions

Group 1: To detect a 10% absolute difference in the prescribing rate of second-line antibiotics after one year, with a significance level of 5% and a power of 90%, a sample size of 65 practices per gr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: General practicioners with the willingness to participate in the four Network regions (Baden-Wuerttemberg, Bavaria, Berlin/Brandenburg, Thuringia).

Exclusion criteria

Exclusion criteria: Private practices

Design outcomes

Primary

Measure	Time frame
Rate of second-line antibiotics prescribed for UTIs at the practice level after 12 months of study, based on aggregated data	—

Secondary

Measure	Time frame
Reduction in prescription rate of total antibiotics for the treatment of UTI as a result of the acceptance of guideline information by the intervention practices.	—

Countries

Germany

Contacts

Public ContactChristiane Wagner

Institut für Allgemeinmedizin Universitätsklinikum Würzburg

Wagner_C2@ukw.de0931-201-47804

Outcome results

None listed