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Treatment exit options for non-infectious uveitis

Treatment exit options for non-infectious uveitis - TOFU

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00020382
Enrollment
4000
Registered
2020-02-18
Start date
2019-08-12
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-infectious uveitis of the posterior segment with or without immunomodulatory treatment

Interventions

Group 1: Disease courses of patients with non-infectious uveitis of the posterior segment

Sponsors

Universitätsklinikum Bonn
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Male or female subjects who are =18 years of age, on the day of signing informed consent - Ability to consent - Non-infectious intermediate, posterior or panuveitis or retinal vasculitis

Exclusion criteria

Exclusion criteria: - Missing or unwilling to consent - Any prior therapy with DMARDs - Intravitreal therapy with dexamethasone, VEGF-Inhibitors, triamcinolone or sirolimus in the last 6 months - Intravitreal therapy with fluocinolone acetonide or methotrexate in the last 36 months - Intraocular surgery within the last 6 months - Severe opacities of cornea, lens or vitreous that preclude assessment of inflammatory activity of the posterior pole - Conceivable inability to attend regularly at participating centre

Design outcomes

Primary

MeasureTime frame
Remission of disease and reduction or discontinuation of immunomodulatory treatment without relapse.

Secondary

MeasureTime frame
Patient reported outcomes, quality of life (QoL)

Countries

Austria, Belgium, Germany, Netherlands, Spain

Contacts

Public ContactJennifer Dell

Universitäts-Augenklinik Bonn

jennifer.dell@ukbonn.de0228 287 15948

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026