perioperative alterations of macro- and microcirculation
Conditions
Interventions
Group 1: Measurements are performed at four predefined time points: t0: steady state before surgical incision, t1: 2h after surgery, t2 6 h after surgery, t3: morning after surgery).
At these time po
Sponsors
Klinik für Anästhesiologie, Intensiv-, Notfallmedizin, Transfusionsmedizin und Schmerztherapie Evangelisches Klinikum Bethel gGmbHv. Bodelschwinghsche Stiftungen Bethel
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - elective major abdominal surgery with a duration of = 2h (including general, abdominal, gynecological, urological surgery) - planned postoperative monitoring in a monitoring ward - placement of arterial and central venous catheter - written informed consent
Exclusion criteria
Exclusion criteria: - age < 18 years - pregnancy - vasculitis - peripheral artery disease (Fontaine IIb or more severe) - no written informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of microcirculatory alterations postoperatively after major abdominal surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are the individual proportions of patients who developed abnormal capillary refill time, mottling score, lactate, and central venous oxygen saturation (each marker individually). Additional endpoints are the proportion of patients with microcirculatory impairment (any vs. none and each marker individually) at each measurement point. | — |
Countries
Germany
Contacts
Public ContactMoritz Flick
Klinik und Poliklinik für AnästhesiologieZentrum für Anästhesiologie und Intensivmedizin Universitätsklinikum Hamburg-Eppendorf
Outcome results
None listed