Role of the subthalamic nucleus for learning simple stimulus-response associations - a multi modal analysis using LFP and EEG data

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00020220

Enrollment

Registered

2020-07-07

Start date

2021-01-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: Day 1 – Experiment: 1 Participants learn to associate three tones with a specific motor response or withholding a motor response. Day 2 – Experiment 2: Participant again learn to associate th

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Parkinson patients undergoing implantation of deep brain stimulation system at the Evangelisches Krankenhaus Oldenburg, followed by a period of time during which DBS leads remain externalized. Moreover inclusion criteria encompass: Becks Depression Inventory 130, Mini Mental State > 23

Exclusion criteria

Exclusion criteria: acute psychiatric disorders, hearing disability/deafness, increased risk of infection

Design outcomes

Primary

Measure	Time frame
The primary goal is to determine whether stimulus-response associations are represented within the activity of the subthalamic nucleus. In order to assess these hypothesis we will measure and analyze behavioral-, EEG-, and local field potential data.	—

Secondary

Measure	Time frame
The secondary goal is to determine whether activity of the nucleus subthalamicus is predictive of the successful selection of a correct association. In order to assess these hypothesis we will measure and analyze behavioral-, EEG-, and local field potential data.	—

Countries

Germany

Contacts

Public ContactKarsten Witt

Carl von Ossietzky Universität OldenburgFakultät VI - Medizin und GesundheitswissenschaftenDepartment für Humanmedizin

karsten.witt@uol.de+49 (0)441 236 649

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026