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Influence of sedation depth, cumulative sedative dose, and regional oxygen saturation on post intensive inpatient cognitive performance in patients with acute respiratory failure

Influence of sedation depth, cumulative sedative dose, and regional oxygen saturation on post intensive inpatient cognitive performance in patients with acute respiratory failure

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00019953
Enrollment
100
Registered
2020-01-03
Start date
2020-01-02
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J80.0

Interventions

Group 1: In sedated patients with ARDS, sedation depth and regional oxygen saturation are measured during the sedation period using non-invasive monitoring techniques (adhesive electrodes applied to t

Sponsors

Universitätsmedizin GöttingenKlinik für Anästhesiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 91 Years

Inclusion criteria

Inclusion criteria: Patient of Ward 0119 (w / m / d) Age> 18 years <91 years Diagnosis of an ARDS Existence of valid information There is a valid consent

Exclusion criteria

Exclusion criteria: Rejection of participation Lack of consent Age 91 years Lack of cooperativity in JH-ACE testing (vigilance disorder, delirium, aphasia) Impossibility of JH-ACE testing due to limited knowledge of the German language

Design outcomes

Primary

MeasureTime frame
cognitive performance at the end of the intensive care stay by means of a cognitive questionnaire (John Hopkins' Adapted Cognitive Exam)

Secondary

MeasureTime frame
Depth of sedation during the sedation phase in the intensive care unit recorded using non-invasive technology (Sedline, Masimo) Cumulative sedative dose as a summation of all sedatives during the intensive care stay taken from the digital documentation system Regional oxygen saturation during the sedation phase in the intensive care unit is measured using non-invasive technology (O3, Masimo).

Countries

Germany

Contacts

Public ContactLars-Olav Harnisch

Universitätsmedizin GöttingenKlinik für Anästhesiologie

lars-olav.harnisch@med.uni-goettingen.de05513963579

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026