Development-dependent aspects of theta-phase gamma-amplitude coupling and their role in interference control in children with ADHD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00019950

Enrollment

Registered

2019-12-04

Start date

2020-01-06

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F90

Interventions

Group 1: children and adolescents with ADHD: 3 sessions: 1.Informed consent and diagnostics

2. EEG session with 64 channel EEG during n-back-, flanker- and continuous performance task (CPT)

3. MRI session with structural MRI, diffusion-tensor-imaging (DTI) and functional MRI in resting state (resting state fMRI). The Data for Study Arm 1 are collected in the Study E-Stim ADHD CIV-17-09-

3. MRI session with structural Magnetic Resonance Imaging (MRI), diffusion-tensor-imaging (DTI) and functional MRI in resting state (resting state fMRI). Group 3: healty adults: 3 sessions: 1.Informe

3. MRI session with structural Magnetic Resonance Imaging (MRI), diffusion-tensor-imaging (DTI) and functional MRI in resting state (resting state fMRI).

Eligibility

Sex/Gender

All

Age

10 Years to 30 Years

Inclusion criteria

Inclusion criteria: Healthy children and adolescents at the age of 10-18, healthy adults at the age of 23-30 and children and adolescents with ADHD at the age of 10-18 years.

Exclusion criteria

Exclusion criteria: IQ<80, birthweight < 2500gr., born before the 37th week of pregancy, past or present neurological diseases/brain surgery, history of craniocerebral injury with loss of consciousness, dermatological diseases of the scalp, heart disease, concurrent neurofeedback therapy; Additional exlusion criteria for participating in the MRI-measurement are metal implants, other unremovable metal objects in or at the body and pregnancy.

Design outcomes

Primary

Measure	Time frame
number of errors, accuracy and reaction times in n-back-, flanker- and continuous performance task; TGC (Theta-Phase Gamma-Amplitude Coupling)	—

Secondary

Measure	Time frame
functional resting state MRI, density of grey and white matter of the cortex in qmm	—

Countries

Germany

Contacts

Public ContactHannah Brauer

Zentrum für Integrative Psychiatrie gGmbH Campus Kiel Klinik für Kinder- und Jugendpsychiatrie und -psychotherapie

Hannah.Brauer@ukhs.de+49 431 500 98 318

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026