F60.31
Conditions
Interventions
Group 1: Borderline patients (age between 18-50 years) undergo the following testing procedures
(1) Clinical-diagnostic measurements
- Diagnosis and characterization of the borderline personality di
dimensional: Criterion A by the semi-structured interview for the section III of the DSM-5 level of personality functioning, criterion B by the questionnaire personality inventory for section III of t
Sponsors
Lehrstuhl für Klinische Psychologie und Psychotherapie, Ludwigs-Maximilians-Universität München
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: - Willingness to cooperate - consenting capacity Additional criteria for the borderline sample: - Current BPS diagnosis (=5 DSM-5 BPS criteria),
Exclusion criteria
Exclusion criteria: - Chronic physical and cardiovascular diseases - BMI 30 Additional criteria for the borderline sample: - Regular medication (other than on-demand medication, regular use of an SSRI/SNRI group antidepressant, acute pain medication >500 mg). - current drug abuse and/or drug dependence in the last 6 months and - bipolar disorder, schizophrenia or organic disorders (lifetime). Additional criteria for the healthy sample: - Any mental disorder (lifetime) and 500 mg).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Aggregated interoceptive measure consisting of four components of interoceptive body perception and two modalities (see secondary target criteria). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome: 1. interoceptive sensitivity measured using the questionnaire "Multidimensional Assessment of Interoceptive Awareness", "Scale of Body connection" and "Survey of Body areas" 2. interoceptive awareness measured by the difference between the heartbeat perception score and subjective performance assessment in the heartbeat task, 3. interoceptive accuracy measured via the heartbeat perception score in the heartbeat task, and 4. cortical representation of interoceptive body signals measured over the mean amplitude of the heart beat-evoked potentials (HEPs) at rest as well as during the interoception and exteroception task. 5. mediation of the association between traumatic childhood experiences (CECA trauma severity) and emotional regulation ability (P300 amplitude in the condition regulating vs. viewing during the emotional regulation task) by interoceptive body perception (aggregated by the four components of interoceptive body perception; see point 1). 6. mediation of the association between traumatic childhood experiences (CECA trauma severity) and emotional regulatory capacity (mentalization score in the reflective-functioning questionnaire) through interoceptive body perception (aggregated via the four components of interoceptive body perception; see point 1). | — |
Countries
Germany
Contacts
Public ContactSarah Back
Lehrstuhl für Klinische Psychologie und Psychotherapie Ludwig-Maximilians-Universität München
Outcome results
None listed