Influence of breast milk versus formula milk on the time the ductus arteriosus closes in preterm infants

Influence of breast milk versus formula milk on the time the ductus arteriosus closes in preterm infants - DUCTUS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00019919

Enrollment

120

Registered

2020-01-17

Start date

2020-12-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Q25.0

Interventions

Group 1: Exclusive feeding with donor-milk until own mothers-milk is available in preterm infants born between 28 0/7 and 32 0/7 weeks of gestation (postmenstrual age) Group 2: Exclusive feeding wit

Eligibility

Sex/Gender

All

Age

0 Days to 7 Days

Inclusion criteria

Inclusion criteria: 28 0/7 - 31 6/7 wks gestation

Exclusion criteria

Exclusion criteria: • SGA < 3. centile • medically / surgically closed PDA • congenital problems of the GI-tract • congenital heart defect, • asphyxia

Design outcomes

Primary

Measure	Time frame
Gut perfusion determined by ultrasound doppler blood-flow velocity in cm/s in the mesenteric superior artery on postnatal days 1,3,5,7 and at discharge	—

Secondary

Measure	Time frame
Progress of PDA-closure (Day of closure by ECHO-cardiographie) Near infrared Spectroskopie (NIRS) of right lower abdomen (% Oxygen saturation) at postnatal days 1,3,5,7 and at discharge. Body composition determined by "Peapod" at at postnatal days 1,3,5,7 and at discharge, if possible on clinical assessment	—

Countries

Germany

Contacts

Public ContactAndreas W. Flemmer

Klinikum der Universität München, Dr. von Haunersches Kinderspital; Neonatologie

Andreas.Flemmer@med.uni-muenchen.de+49-89-4400-72800

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026