Small-angle X-ray scattering of LDL-subfractions

Small-angle X-ray scattering of LDL-subfractions - LDLSAXS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00019895

Enrollment

Registered

2020-10-15

Start date

2020-03-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers E78

Interventions

Group 1: Separation of plasma by its density via ultracentrifugation into the lipoproteinfractions LDL and HDL, as well as into 6 and 3 subfractions of LDL and HDL, respectively. Eventually small angl

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) high triglycerides (>500mg/dl), 2) normal triglycerides (<100mg/dl)

Exclusion criteria

Exclusion criteria: 2) Serious liver or kidney-disorders, pregnancy, acute serious desease, TSH non in the reference range

Design outcomes

Primary

Measure	Time frame
transition states in the LDL subfractions, measured by small-angle X-ray scattering	—

Secondary

Measure	Time frame
hypothesis: Hypertriglyceridemic LDL have a significant different behaviour	—

Countries

Germany

Contacts

Public ContactKarl Winkler

Universitätsklinikum FreiburgInstitut für klinische Chemie und Laboratoriumsmedizin

karl.winkler@uniklinik-freiburg.de49 761 27033160

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026