Healthy
Conditions
Interventions
Group 1: This is a cross-sectional study. The study includes extensive health and nutritional medical diagnostics. Therefore, probands who eat omnivorous are recruited. At least 30 subjects are includ
Sponsors
Leibniz Universität Hannover, Institut für Lebensmittelwissenschaft und Humanernährung
Eligibility
Sex/Gender
All
Age
25 Years to 46 Years
Inclusion criteria
Inclusion criteria: - healthy, consenting men and women - Age: 25-46 years old - Stable weight for at least half a year (± 3 kg), BMI 20-28 kg/m² - Same form of nutrition for at least one year - non-smokers
Exclusion criteria
Exclusion criteria: - acute febrile infections - severe chronic diseases (cancer, diabetes type 1, etc.), manifest cardiac circulatory disease, renal insufficiency, liver diseases - chronic diseases of the gastrointestinal tract (ulcerative colitis, Crohn's disease, pancreatic insufficiency) - known endocrine and immunological ailments - regular intake of laxatives - Drug, alcohol and medication abuse - Probands who were unable to give their consent - Simultaneous participation in another clinical study or participation within the past 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4+/CD8+ T-cell ratio | — |
Secondary
| Measure | Time frame |
|---|---|
| - Indices for subclinical inflammation: PLR, NLR, SII - Parameters of glucose metabolism (fasting glucose, insulin, HbA1c, HOMA) - Parameters of fat metabolism (LDL, HDL, TC, TG) - Parameters of iron metabolism (iron, Transferrin, Ferritin) - potassium, calcium, magnesium - vitamins B2, B6, 4cB12 (vitamin B12 in serum, Holo-TC, homocysteine, methylmalonic acid) - calcidiol, parathyroid hormone - Interleukin 1, 6, IFN?, TNFa, hs-CRP, - Amino Acid Profile, ADMA - folic acid, zinc, ec-folate - Large blood count - Oxidative stress, creatinine - Sirtuins (1, 3, 5) - leptin, adiponectin - Creatinine, GGT, GOT, GPT - histamine - albumin, total protein, uric acid - Acid-base-state (NAE, pH-value urine) - Iodine in urine - Fatty acid profile including O-3-index (relative content of EPA and DHA) in erythrocyte membranes - health status; e.g. SF 36 - Nutritional behaviour; Nutrition diary, FFQ - Calculation of the PRAL value from the nutrition questionnaires - Physical activity, e.g. “Freiburger” questionnaire - Anthropometric data (size, weight, BMI, waist circumference, blood pressure, pulse) - body composition - pulse wave velocity | — |
Countries
Germany
Contacts
Public ContactAnja Bruns
Leibniz-Universität Hannover, Institut für Lebensmittelwissenschaft und Humanernährung
Outcome results
None listed