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Application of two neurophysiological tests to identify individual characteristics of patients suffering from borderline personality disorder with and without comorbid post-traumatic stress disorder

Application of two neurophysiological tests to identify individual characteristics of patients suffering from borderline personality disorder with and without comorbid post-traumatic stress disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00019851
Enrollment
25
Registered
2019-11-21
Start date
2019-12-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F60.3 F43.1

Interventions

Group 1: Observational study: patients suffering from borderline disorder with and without comorbid posttraumatic disorder with or without naltrexone treatment During treatment, we will conduct the „
Garbutt et al., 2009
Kampov-Polevoy et al., 1999) as well as the Qb-Atest (FDA approved
www.qbtech.com) – shortly after the admission. Moreover, patients will be asked to answer several questionnaires with respect to severity of the illness (with respect to severity and frequency of diss

Sponsors

Zentralinstitut für Seelische Gesundheit
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: - Patients suffering from borderline personality disorder and/or - posttraumatic stress disorder -German-speaking -Capacity to provide informed consent -Written Informed Consent -negative breath analysis for alcohol

Exclusion criteria

Exclusion criteria: - comorbid substance use disorder - non German-speaking - lack of capacity to provide informed consent - lack of written informed consent - blindness -neurological deficits influencing the eye-tracking - e.g. no smell or taste

Design outcomes

Primary

MeasureTime frame
The aim of the study is to identify clinical phenotypes and parameters to deepen the biological underpinnings of borderline disorder (focusing the opioidergic and dopaminergic system) as well as to predict treatment response to naltrexone in borderline disorder with and without comorbid posttraumatic disorder

Countries

Germany

Contacts

Public ContactMalte Bumb

Zentralinstitut für Seelische Gesundheit

,alte.bumb@zi-mannheim.de062117033502

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026