Colonization / Transmission of MDRO (Multi drug resistant organisms) P36
Conditions
Interventions
Group 1: Hand Hygiene care policy in 2_MRGN colonized Infants (Term and Preterm) (Intervention):
During 12 months, Infants colonized with 2_MRGN pos bacteria are nursed with normal Hand Hygiene care
Sponsors
UNIVERSITÄTSKLINIKUM WÜRZBURG, Kinderklinik und Poliklinik
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion of an entire neonatal unit. Analyses of microbiotic Screening-data, not Patient specific data
Exclusion criteria
Exclusion criteria: Exclusion of a Center in case of missing microbiotic surveillance (KRINKÒ)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Endpoint is the rate of blood kulture pos. infections with gram neg. bacteria in all term- and preterm infants, in wich a Screening was performed (non- inferiority). This endpoint is defined clinically along NEO-KISS-criteria (two signs of Sepsis + one laboratory sign of Inflammation (e.g. CrP >10mg/dl) and proof of a gram neg. pathogen in bood culture) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are i.a. the transmission rate of 2_MRGN bacteria. Transmission is postulated if two children are colonized are infected with the same bacteria (with same resistance spectrum) in spaciotemporal connection. Other secondary endpoints are the transmissionrate of other bacteria included in the KRINKO-Screening, rate of all blood-stream infections and clinical infections, number of antibiotic cycles, use of antibiotics of the last resort (e.g. carbapenemes) and consumption rate of antibiotics and desinfectants. | — |
Countries
Germany
Contacts
Public ContactKirstin Faust
Universität zu LübeckUniversitätsklinikum Schleswig Holstein, Campus LübeckKlinik für Kinder- und Jugendmedizin
Outcome results
None listed