F10.2 F32.0 F32.1 F32.2 F32.8 F32.9
Conditions
Interventions
Group 1: Intervention group: psychoeducation, one-hour intervention, plus diary for day structuring over 6 weeks (DAILY program)
Group 2: Control group: sham-psychoeducation, one-hour sham condition,
Sponsors
Klinik der Universität München
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: All persons on whom the below exclusion criteria do not apply. Special attention is paid to the assessment of the test persons' ability to understand the scope of the study. Subjects are only included in the study if they can assess the nature and scope of the investigations. Written consent is required for inclusion. The study is conducted in accordance with the principles of the Declaration of Helsinki with its amendments of Tokyo, 1975, Hong Kong, 1989, Somerset West, 1996, Seoul, 2008 and Fortaleza, 2013. The subjects must suffer from alcohol dependence and depression. The MDD diagnosis must meet the following criteria for our study: Only unipolar depression, only recurrent depression with at least mild depression. Currently, there should be no psychotic symptoms or acute suicidal tendencies.
Exclusion criteria
Exclusion criteria: Inability to give consent, pregnancy, current shift work, intellectual, neurological or physical impairment, other psychiatric illness (except alcohol addiction and MDD), other substance addictions (except alcohol), blindness, dependence on help with eating or going to bed (e.g. like bedridden patients).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary variable surveyed is the relapse rate for alcohol addiction in the first four weeks after discharge from withdrawal. It is measured at the beginning and the end of the study by questionnaires (AUDIT, EuropASI), blood values (GOT, GPT, ?-GT, MCV, MCH, CDT) and retrograde self-disclosure of the subjects (Alcohol Timeline Followback 30). In addition, the participants enter possible relapses in a diary. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary variables are depressive mood, sleep quality, chronotype, self-efficacy, and general physical well-being of the subjects in the first four weeks after withdrawal. The secondary target criteria are measured at the beginning and the end of the study as follows: Depressive mood - Hamilton Depression Scale (HAM-D), inventory of depressive symptoms (IDS-SR), Sleep Quality - Pittsburgh Sleep Quality Index (PSQI), Chronotype - Munich Chronotype Questionnaire (MCTQ), Self-efficacy - General expectation of self-efficacy (SWE), Physical well-being - Health status questionnaire (SF-36). | — |
Countries
Germany
Contacts
Public ContactDominic Landgraf
AG Circadiane Biologie, Klinik für Psychiatrie und Psychotherapie der Universität München
Outcome results
None listed