Predictive factors of persistence of ascites after TIPS implantation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00019015

Enrollment

400

Registered

2019-12-20

Start date

2020-04-23

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K74

Interventions

Group 1: Patients with TIPS implantation: Analyses of serological parameters and parameters of primary and secondary hemostatsis

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients with TIPS implantation

Exclusion criteria

Exclusion criteria: Patients without TIPS implantation

Design outcomes

Primary

Measure	Time frame
a) Analysis of ADH after TIPS implantation and correlation with the persistence of ascites after TIPS implantation b) Analysis of predictive factors for persistence of ascites after TIPS implantation c) Influence of the oncotic and hydrostatic pressure on the persistence of ascites after TIPS implantation d) Analysis of the baseline activation status of platelets before TIPS implantation e) Influence of the stent graft on platelet function f) Influence of antithrombin and clotting factor VIII on the development of TIPS thrombosis	—

Measure

Time frame

a) Analysis of ADH after TIPS implantation and correlation with the persistence of ascites after TIPS implantation b) Analysis of predictive factors for persistence of ascites after TIPS implantation c) Influence of the oncotic and hydrostatic pressure on the persistence of ascites after TIPS implantation d) Analysis of the baseline activation status of platelets before TIPS implantation e) Influence of the stent graft on platelet function f) Influence of antithrombin and clotting factor VIII on the development of TIPS thrombosis

—

Secondary

Measure	Time frame
a) Correlation of ADH with degree of liver dysfunction (clinical and laboratory parameter and scores) b) Correlation of ADH with the oncotic and hydrostatic pressure and indication for TIPS implantation (ascites vs. varices) c) Correlation of platelet function, antithrombin and clotting factor VIII with liver function d) c) Correlation of platelet function, antithrombin and clotting factor VIII with indication for TIPS implantation (ascites vs. varices)	—

Measure

Time frame

a) Correlation of ADH with degree of liver dysfunction (clinical and laboratory parameter and scores) b) Correlation of ADH with the oncotic and hydrostatic pressure and indication for TIPS implantation (ascites vs. varices) c) Correlation of platelet function, antithrombin and clotting factor VIII with liver function d) c) Correlation of platelet function, antithrombin and clotting factor VIII with indication for TIPS implantation (ascites vs. varices)

—

Countries

Germany

Contacts

Public ContactDominik Bettinger

Universitätsklinikum FreiburgKlinik für Innere Medizin II

dominik.bettinger@uniklinik-freiburg.de0761/270-34010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026