Personality trait Perception Recurrence I48
Conditions
Interventions
Group 1: Asymptomatic to oligosymptomatic patients (EHRA I-IIa).
Within the clincial routine a transesophageal echocardiography procedure was performed before cardioversion/ pulmonary vein isolation
Sponsors
Universitätsklinikum Mannheim
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: male and female pts = 18 years, with atrial fibrillation, written informed consent
Exclusion criteria
Exclusion criteria: Unstable Angina pectoris / Acute Myocardial Infarction / Cardiogenic Shock Indications for operative coronary revascularization (bypass surgery) Stroke or TIA Resting heart rate <50 beats per minute Presence of a pacemaker / AICD and other metallic implants Valve vitium with indication for surgery Sick sinus syndrome, SA block, AV block III Uncontrolled hypertension Severe hypotension (<90 / 50mmHg) Severe hepatic insufficiency Patients with heart failure NYHA class III - IV Pacemaker dependency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptoms (measurement method: questionnaire, interview) Aortic distensibility (measurement method: echocardiography transthoracic / transesophageal) Pulse wave velocity and augmentation index (measurement method: pulse wave analysis using a tonometrically recorded pulse curve). The primary endpoint is collected only once at the beginning of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory measured parameters for oxidative stress and inflammation (50 ml blood, 3xLi-Hep, 3xCitrate, 3xEDTA): VCAM-1, ICAM-1, MCP-1, TNF-alpha, IL-6, hs-CRP (measurement method: ELISA) Personality trait (measurement method: questionnaire 5 BT, interview). The secondary endpoint is collected only once at the beginning of the study. | — |
Countries
Germany
Contacts
Public ContactAnna Hohneck
Universitätsklinikum Mannheim I. Medizinische Klinik - Kardiologie
Outcome results
None listed