Proteomic signatures predictive of left ventricular reverse remodelling upon restored aortic or mitral valve function

Proteomic signatures predictive of left ventricular reverse remodelling upon restored aortic or mitral valve function - ProCaR : Proteomics of Cardiac Remodelling

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00018986

Enrollment

200

Registered

2019-11-12

Start date

2020-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I34 I35

Interventions

Group 1: Patients with aortic- and mitral regurgitation included in the study will undergo cardiac echocardiography prior to surgery as well as during follow-up in 6 and 12 months. In addition to ech

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients with the diagnosis of: mitral or aortic regurgitation, benign cardiac tumors, tricuspid valve regurgitation, isolated ascendig aneurysm without concomittant aortic regurgitation

Exclusion criteria

Exclusion criteria: Isolated coronary artery disease requireing surgical revascularisation missing consent to take part in the study

Design outcomes

Primary

Measure	Time frame
Biochemical and echocardiographic markers in relation to cardiac function after surgical corrective therapy in patients with aortic or mitral regurgitation.	—

Secondary

Measure	Time frame
no secondary endpoints defined	—

Countries

Germany

Contacts

Public ContactJasmin Hasmik Shahinian

Universitaets-Herzzentrum Freiburg/Bad Krozingen Abteilung für Herz- und Gefässchirurgie

jasmin.shahinian@universitaets-herzzentrum.de0761270-28180

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026