Zoonotic Clostridium difficile Infections Acquired in the Community

Zoonotic Clostridium difficile Infections Acquired in the Community - ZODIAC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00018982

Enrollment

900

Registered

2019-10-24

Start date

2020-02-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

community-associated Clostridioides difficile infection A04.7

Interventions

Group 1: Patients with community-associated Clostridioides difficile infection are questioned once with a standardized questionnaire on zoonotic risk factors and confounders. Group 2: Frequency matche

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - visit to general practitioner or hospital with symptoms prompting C. difficile testing - detection of toxigenic C. difficile - adult (18 years or older)

Exclusion criteria

Exclusion criteria: - healthcare facility stay in those 4 weeks prior to symptoms

Design outcomes

Primary

Measure	Time frame
This case-control study aims at assessing potential risk factors for C. difficile detection in patients without hospital contact in the previous 4 weeks.	—

Secondary

Measure	Time frame
Exposures will be identified after informed consent with a standardized questionnaire.	—

Countries

Germany

Contacts

Public ContactKlaus Stark

Robert Koch-Institut

zodiac@rki.de0049 30 18754 5010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026