L70
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Knowledge of German language Android- or iOS-Smartphones all sexes Acne: clinically proben (facial Acne papulopustulosa or Acne papulopustulosa et comedonica), mild to moderate (Grade 2 - 8 according Leeds Scale of Acne Grading), al least 10 inflammatory lesions, no treatment other than OTC control group: healthy skin of all types
Exclusion criteria
Exclusion criteria: medical acne treatment antibiotics pre- or probiotics pregnancy, breast feeding underweight or obesity (BMI < 18,5 kg/m2, BMI = 30 kg/m2) inflammatory skin condition other than acne intestinal diseases malignant diseases Type 1 and Type 2 Diabetes mellitus food intolerance/allergies autoimmune diseases eating disorders drug addiction shift work
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne: Improvement of skin determined by: i) inflammatory lesions (face), ii) acne score, iii) sebum quantity and quality (before and after nutrition intervention) Skin healthy individuals: Improvement of skin determined by: i) self assessment. ii) sebum quantity and quality (before and after nutrition intervention) | — |
Secondary
| Measure | Time frame |
|---|---|
| Applicability of personalized, low-glycemic nutrition advice in treatment of acne patients and other acne-relevant parameters to quantify impact on skin; inflammatory parameters (lipids, immense cells, growth hormones in blood), microbiome before and after nutrition intervention, self assessment with relation to skin and wellbeing | — |
Countries
Germany
Contacts
Beiersdorf AG, Front End InnovationManager Gut-to-Skin Axis