Predictability of response and compatibilty of systemic therapy using the Maximum Liver Function Capacity (LiMAx) test in patients with hepatocellular carcinoma (HCC)

Predictability of response and compatibilty of systemic therapy using the Maximum Liver Function Capacity (LiMAx) test in patients with hepatocellular carcinoma (HCC) - systemic therapy LiMAx

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00018886

Enrollment

Registered

2019-12-09

Start date

2017-12-21

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C22

Interventions

Group 1: The following data is collected 1. demographic patient characteristics and comorbidities 2. LiMAx test results 3. Liver stiffness, measured by transient hepatic elastography 4. degree of liv

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients (m / f) = 18 years with HCC and indication for systemic treatment as determined by the responsible tumor board - written consent of the participating patients - No contraindications for performing a LiMAx test

Exclusion criteria

Exclusion criteria: - no written consent of the participating patients - contraindications for performing a LiMAx test

Design outcomes

Primary

Measure	Time frame
Predictability of response and compatibilty of systemic therapy of HCC using LiMAx test	—

Secondary

Measure	Time frame
1) Correlation of the results of the LiMAx test with the Child-Pugh score in patients with HCC 2) extent of decrease or regeneration of liver function after systemic therapy according to LiMAx test 3) Comparison of the results of the LiMAx test with the ART score regarding the prognostic relevance	—

Countries

Germany

Contacts

Public ContactStefanie Frank

Universitätsklinikum Leipzig AöR, Klinik und Poliklinik für Gastroenterologie, Hepatologie, Infektiologie, Pneumologie, Sektion Hepatologie

leber@uniklinik-leipzig.de0341-97-12330

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026