K00-K14
Conditions
Interventions
Group 1: Ridge preservation
(placement of the implant 5 months after tooth extraction and filling with biomaterials)
Group 2: Early Implant Placement (Placement of the implant 2 months after tooth
Sponsors
Clinic of Reconstructive DentistryCenter of Dental MedicineUniversity Zurich
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Periodontally healthy individuals with at least 20 years of age 2. Good oral hygiene (BOP & PlI = 20%) 3. Patients with a failing single tooth in the maxilla and mandible, from second premolar to second premolar 4. At least 50% of the buccal bone plate intact after tooth extraction 5. At least one neighboring natural tooth 6. Presence of antagonist 7. Capability to comply with the study procedures 8. Informed Consent as documented by signature
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women 2. Known or suspected non-compliance, drug or alcohol abuse 3. Smokers (>10 cigarettes/day) 4. Systemic or local conditions presenting a contraindication to implant treatment 5. Currently taking drugs that influence bone metabolism 6 .Use of bisphosphonates in the last 4 years 7. History of malignancy, radiotherapy or chemotherapy for malignancy in the past 5 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be contour changes (mm) at the buccal aspect of the extraction site from pre-tooth extraction (baseline) to 5 months later by volumetric analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| • profilometric outcomes (horizontal changes) at screening, T0, T1, T2, T3, T4, T5, T6. • clinical parameters (probing depth, bleeding on probing, plaque index, keratinized mucosa) at screening, T3, T4, T5, T6 by using a dental probe • aesthetic (PES, WES) at screening, T3, T4, T5, T6 by dentist's score • marginal bone level and buccal bone thickness at T0, T2, T3, T6 by radiographic methods •i mplant survival at T3, T4, T5, T6 by observing whether the implant is in place or not • patient-reported outcome measures at T0, T1, T2, T3, T4, T5, T6 by questionnaires • costs at T3, T4, T5 and T6. • need for additional Guided Bone Regeneration at T1, T2. • need for an additional soft tissue grafting procedure at T2. • Dentist's VAS score for ease of treatment for the dentist at T0, T1, T2. • Dentist's VAS for Treatment Satisfaction for the dentist at T3,T4,T5,T6 • Technical parameters at T3, T4,T5,T6 by using USPHS criteria | — |
Countries
Belgium, Switzerland
Contacts
Public ContactDaniel Thoma
Clinic of Reconstructive DentistryCenter of Dental MedicineUniversity Zurich
Outcome results
None listed