The use of microscopic optical coherence tomography in patients with Fuchs corneal endothelial dystrophy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00018848

Enrollment

Registered

2019-12-11

Start date

2019-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H18.5

Interventions

Group 1: Cornea explants of patients with corneal endothelial dystrophy will be scanned by mOCT (microscopic coherence tomography). Group 2: Cornea explants of healthy patients will be scanned by mOCT

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients - male, female, older than 18 years, able to give written consent - availaben written consent - diagnosed with Fuches endothelial dystrophy - culture time maximum 50 days, preferably less than 35 days - consent of the donor or next relative for usage in this study - not eligible for transplantation

Exclusion criteria

Exclusion criteria: Patient: - known infectious diseases - other ophthalmological diseases than FED or Cataracta - no consenct for scientific studies - culture lenght > 50 days

Design outcomes

Primary

Measure	Time frame
To obtain detailed information about ultrastructural changes in cornea explants of healthy individuals and FED-patients. The corneas of FED-patients are obtained when these patients undergo surgical treatment (Descemet membrane endothelial keratoplasty). The corneas of healthy individuals are obtained from the Gewebebank Mecklenburg-Vorpommern. These are corneas stored for scientific purpose.	—

Countries

Germany

Contacts

Public ContactMario Matthaei

Zentrum für Augenheilkunde, Universitätsklinikum Köln

mario.matthaei@uk-koeln.de0221 478 4313

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026