F51.0
Conditions
Interventions
Group 1: Patients with insomnia will be treated with CBT-I and will undergo MRI measurement before and after treatment.
Sponsors
Universitätsklinikum Freiburg, Klinik für Psychiatrie und Psychotherapie
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: - written informed consent - meeting research diagnostic criteria for insomnia disorder according to DSM 5 - Age between 18 and 65 years
Exclusion criteria
Exclusion criteria: - unstable, progressive or degenerative medical condition - acute pain or poorly managed chronic pain, if causally linked to insomnia - suicidality - uncontrolled psychiatric condition requiring immediate treatment outside of study - abuse or dependency of alcohol, medication or any illegal substance within the past year - vidence of sleep disorders except insomnia disorder (i.e., AHI>15, PLMS index with arousal > 5) - evidence of intellectual disability - intake of sleep medication 2 weeks prior to and during the study treatment until the last therapy session - other psychotherapy within the last 3 years - history of brain damage - MRI contraindications - pregnancy and lactation period - insufficient fluency in German to complete the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of BOLD-signal and GABA levels in brain regions using fMRI and MRS before and after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Questionnaires before and after treatment with outcome parameters regarding subjective sleep efficacy, sleep behavior, sleep effort, sleep-related quality of life, psychological flexibility and use of emotion regulation strategies | — |
Countries
Germany
Contacts
Public ContactKai Spiegelhalder
Universitätsklinikum Freiburg, Klinik für Psychiatrie und Psychotherapie
Outcome results
None listed