Deep Brain Stimulation induced Cortical Modulation in Tourette syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00018838

Enrollment

Registered

2019-10-02

Start date

2020-05-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F95.2

Interventions

Group 1: We aim to include patients with Tourette syndrome and bilateral thalamic deep brain stimulation (DBS) electrodes. The study comprises informed consent, completion of psychmetric scales, prepa

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: - Suficient German language skills - Age between 18 and 65 Jahren - Ability to give informed consent - Diagnosis Tourette syndrome (ICD 10) - Thalamic deep brain stimulation

Exclusion criteria

Exclusion criteria: - Suicidal tendencies - Psychotic symptoms - Drug addiction - Pregnancy or nursing period - Severe internistic illness - Severe neurological disorder - Mental retardation - Accomodation via PsychKG §14 - Use of benzodiazepine - Withdrawal of informed consent

Design outcomes

Primary

Measure	Time frame
Changes in EEG frequency bands evoked by thalamic deep brain stimulation. Recordings will follow an ABABAB design. The primary outcome is the EEG signal difference between on and off stimulation.	—

Secondary

Measure	Time frame
Predicition of EEG changes by overlap of volumes of tissue activitated with specific thalamic nuclei.	—

Countries

Germany

Contacts

Public ContactThomas Schüller

Klinik für Psychiatrie und Psychotherapie, Uniklinik Köln

thomas.schueller@uk-koeln.de022147898844

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026