G62.80 G72.80
Conditions
Interventions
Group 1: 50 patients will be examined preoperative and postoperative depending on their health-status within one week during their intensive care unit stay and undergo a clinical neurological examinat
Sponsors
Klinik für Anästhesiologie, Intensiv- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age = 18 years, written informed consent, sufficient knowledge of German, elective cardiac surgery with heart-lung machine
Exclusion criteria
Exclusion criteria: Employees of the investigators or of the institution who are involved in the conduct of this or other clinical trials, participants who are unable to provide informed consent due to language, psychological or somatic reasons, participants with pre-existing, already diagnosed polyneuropathy, HbA1c> 8.5%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the incidence and the time course of the early phase of the CIPNM, assessment of risk factors for the development of a CIPNM, determination of the correlation between neurophysiology and / or nerve morphology and clinical outcome, determination of the degree of neurophysiological and morphological changes, determination of neurophysiological profiles | — |
Secondary
| Measure | Time frame |
|---|---|
| Determination of cytokine profiles during intensive care therapy, evaluation of differences in preoperative baseline values, predictors (e.g. frailty) of patients who will develop a CIPNM in relation to neurophysiological changes | — |
Countries
Germany
Contacts
Public ContactNathalie Malewicz
Klinik für Anästhesiologie, Intensiv- und Schmerzmedizin, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil Bochum
Outcome results
None listed