Reconstruction of a reduced intestinal microbiome after a colonoscopy
Conditions
Interventions
Group 1: 50 subjects are enrolled in the verum group who receive OMNi-BiOTiC® Colonize (dietary supplement), 2x 3g / day, for 30 days.
Group 2: Another 50 subjects receive a placebo.
Sponsors
Institut Allergosan
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Healthy volunteers (no diagnosed bowel disease) Age 50-80 years Consent to participate
Exclusion criteria
Exclusion criteria: Diagnosed, currently clinically relevant disease of the intestine Taking other probiotics Antibiotic therapy in the last 4 weeks Lack of consent to participate in the study Immunosuppressive therapy Age 80 years Taking proton pump inhibitors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the reconstruction of the microbiome immediately after 30 days of intervention, which is analyzed by 16S rRNA microbiome analysis from stool samples. OMNi-BiOTiC® Colonize is used for the management of a reduced intestinal microbiome after a colonoscopy, which was carried out as part of a preventive examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Abdominal discomfort, Abnormalities of bowel movements (determined by Bristol Stool Scale) | — |
Countries
Germany
Contacts
Public ContactSandra Kofler
Institut Allergosan
Outcome results
None listed