Effects on anorectal, urogenital and sexual functioning of operations of the rectum

Effects on anorectal, urogenital and sexual functioning of operations of the rectum - RESEX

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00018082

Enrollment

Registered

2022-03-08

Start date

2019-07-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C20 K51.0

Interventions

Group 1: patient with neoadjuvant Radio- (Chemo-)therapy Group 2: patient without neoadjuvant Radio- (Chemo-)therapy

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: adenocarcinoma of the rectum, 0-16 cm measured from anocutaneous line with histological proof. Planned operation with low anterior resection or intersphincteric resction by proven colitis ulcerosa Age = 18 y

Exclusion criteria

Exclusion criteria: radiatio of pelvic region in medical history metastasized or high grade carcinoma without surgical therapy missing capacity of consent complete urinary incontinence complete fecal incontinence familial adenomatous polyposis- associated carcinoma of rectum emergency operations rectal extirpation operation without primary restored continuity

Design outcomes

Primary

Measure	Time frame
Change in maximum urinary flow measured by uroflowmetry.	—

Secondary

Measure	Time frame
deterioration of anorectal function measured by EORTC QLQ - C30 and -CR 29 function of pelvic muscles measured by Multiple Array Probe Leiden (MAPLe) urogenital function measured by Uroflowmetry, International Consultation of Incontinence Questionnaire (ICIQ) sexual function measured by Female Sexual Function Index (FSFI), International Index of Eredtile Function (IIEF), Derogatis Interview for Sexual Functioning (DISF)	—

Measure

Time frame

deterioration of anorectal function measured by EORTC QLQ - C30 and -CR 29 function of pelvic muscles measured by Multiple Array Probe Leiden (MAPLe) urogenital function measured by Uroflowmetry, International Consultation of Incontinence Questionnaire (ICIQ) sexual function measured by Female Sexual Function Index (FSFI), International Index of Eredtile Function (IIEF), Derogatis Interview for Sexual Functioning (DISF)

—

Countries

Germany

Contacts

Public ContactJohannes Lauscher

Charité Campus Benjamin Franklin

johannes.lauscher@charite.de030 450 522722

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026