Skip to content

Dental and oral health, oral microbiota, neurological parameters and incidence of pneumonia in acute stroke patients – a prospective observational study

Dental and oral health, oral microbiota, neurological parameters and incidence of pneumonia in acute stroke patients – a prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00018063
Enrollment
200
Registered
2019-09-03
Start date
2018-02-26
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I61 I62 I63 I64 J13 J14 J15 J16 J17 J18

Interventions

Group 1: Stroke-Mimics (Patients, who are admitted to the Stroke-Unit with stroke-like symptoms but are not diagnosed with stroke
in-house control group) Group 2: Stroke (Patients who are diagnosed with stroke after inpatient admission to the Stroke-Unit) Group 3: Stroke (Patients who are diagnosed with stroke after inpatient ad

Sponsors

Universitätsklinikum Regensburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - written informed consent - all investigations planned for the first investigation timepoint achievable within 24 h after inpatient admission at the Stroke-Unit

Exclusion criteria

Exclusion criteria: - need for endocarditis prophylaxis - intubation at time of inpatient admission

Design outcomes

Primary

MeasureTime frame
- Oral Health (DMFT index, Approximal Plaque-Index, max. pocket probing depth for each tooth) - demographic parameters - anamnestic parameters (e.g. medical history) - neurological parameters (e.g. stroke localization) - Investigation time points: Baseline (BL): within 24 h of inpatient admission at the Stroke Unit; 48 h: 48 h after BL; 120 h: 120 h after BL

Secondary

MeasureTime frame
- Mikrobiological analyses (culture-dependent as well as culture-independent by means of 16S rRNA Amplicon Sequencing) - Blood analyses (classic infection markers like CRP) - Investigation time points: Baseline (BL): within 24 h of inpatient admission at the Stroke Unit; 48 h: 48 h after BL; 120 h: 120 h after BL

Countries

Germany

Contacts

Public ContactFabian Cieplik

Poliklinik für Zahnerhaltung und Parodontologie Universitätsklinikum Regensburg

fabian.cieplik@ukr.de0941 944 6024

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026