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Controlled, randomized study on the application of air-polishing with a novel application tip for subgingival biofilm removal during supportive periodontal therapy

Controlled, randomized study on the application of air-polishing with a novel application tip for subgingival biofilm removal during supportive periodontal therapy - Novel application of trehalose in the SPT

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
DRKS
Registry ID
DRKS00017844
Enrollment
50
Registered
2019-08-14
Start date
2019-08-14
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.3

Interventions

Group 1: Treatment 1 tooth with air-flow application Group 2: Treatment 1 tooth with sonic instrumentation

Sponsors

DÜRR DENTAL SE
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Two single root teeth per patient with persistent periodontal pockets (ST 5mm/BOP + or 6mm and <10mm) in one jaw, in different quadrants and at a distance of one tooth. - The examination will be performed on 50 patients. - Patient is regularly aware of the supportive periodontitis therapy - It is a periodontal disease with a slow or moderate rate of progression. - A maximum of 20% smokers are to be admitted to the patient collective. - The last antibiotic should have been taken at least 12 weeks ago.

Exclusion criteria

Exclusion criteria: - Taking antibiotics during the study period - Increase of probing depths = 2mm - Development of a periodontal abscess - Pus drainage over the pocket - simultaneous periodontitis treatment elsewhere during the study period - Tooth extraction of the selected teeth - Need for antibiotic prophylaxis - Serious general diseases that have a significant influence on the immune system (e.g. HIV, autoimmune diseases, cancer, poorly controlled diabetes mellitus, etc.) - Haemorrhagic diathesis - taking bisphosphonates or blood-thinning drugs - Presence of pregnancy - Presence of an infectious disease (e.g. hepatitis, HIV) - severely reduced general condition

Design outcomes

Primary

MeasureTime frame
Probe depth reduction after 3 months and after 6 months

Secondary

MeasureTime frame
Attachment gain, reduction of bleeding on probing (BOP) and increase in percentage of healthy periodontium (= 3 mm), subjective pain sensation (visual analogue scale 1-10)

Countries

Germany

Contacts

Public ContactBenjamin Roth

Klinik f. Zahnerhaltung und ParodontologieDep. f. Zahn-, Mund- und Kieferheilkunde, Universitätsklinikum Freiburg

benjamin.roth@uniklinik-freiburg.de0761-27049100

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 18, 2026