The effect of the use of misoprostol on the efficiency of MR-HIFU treatment in women with symptomatic uterine fibroids

The effect of the use of misoprostol on the efficiency of MR-HIFU treatment in women with symptomatic uterine fibroids - Misoprostol and MR-HIFU in UFs.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00017841

Enrollment

Registered

2019-09-10

Start date

2017-07-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D25

Interventions

Group 1: 2 tablets of arthrotec were added vaginally 30 min before HIFU (High-intensity focused ultrasound) treatment. Average time of the entire treatment was 150min. Group 2: Patients with symptomat

Eligibility

Sex/Gender

Female

Age

20 Years to 43 Years

Inclusion criteria

Inclusion criteria: Symptomatic uterus fibroids, fertility disorder

Exclusion criteria

Exclusion criteria: Size of fibroid >13 cm, asymptomatic fibroids, MR contraindications

Design outcomes

Primary

Measure	Time frame
Evaluation of NPV (non-perfused volume) after treatment. Evaluation of time of treatments. NPV is measured after injecting radiological contrast fluid, and NPV is used to determine the area of the necrosis in the tumor. The Duration of each treatment consisted of only the sonication time.	—

Secondary

Measure	Time frame
Evaluation of volume of fibroids in MR scanner 6 MTh after treatment.	—

Countries

Poland

Contacts

Public ContactTomasz Lozinski

Pro-familia Hospital

sekretariat@pro-familia.pl+48662106226

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026