Deprescribing of antipsychotics of patients with dementia in long term care - an intervention study

Deprescribing of antipsychotics of patients with dementia in long term care - an intervention study - READY

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00017831

Enrollment

100

Registered

2019-09-04

Start date

2019-05-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F03

Interventions

Group 1: READY includes patients with advanced dementia who live in long term care, have been receiving an antipsychotic for at least 3 months to treat neuropsychiatric symptoms, and who appear to be

Eligibility

Sex/Gender

All

Age

20 Years to 110 Years

Inclusion criteria

Inclusion criteria: - Person with dementia living in long term care for at least six months; - Person has been treated with at least one AP for at least three months for the treatment of neuropsychiatric symptoms as part of dementia (including sleep disorders), which can be deprescribed with low risk. - Deprescribing AP indicated. - Informed consent of the resident or his legal representative available - Close relative with sufficient knowledge of German ready to participate in the study

Exclusion criteria

Exclusion criteria: - Indication of treatment with AP is not neuropsychiatric symptoms in dementia but e.g. schizophrenia. -Severe disease that makes survival until the end of the study unlikely.

Design outcomes

Primary

Measure	Time frame
The primary endpoint of the study is the estimation of the relative frequency with which anti-psychotics deprescribing recommendations are partially or fully implemented by the treating physician.	—

Secondary

Measure	Time frame
In addition to the investigation of the primary endpoint, the statistical analysis also includes pre-post comparisons with regard to the state of the patients before and after AP therapy. In addition, an analysis of the reasons that prevented physicians from implementing the antipsychotic deprescribing recommendation is performed, supplemented by a description of the patients with and without implementation of the recommendations by descriptive statistics.	—

Measure

Time frame

In addition to the investigation of the primary endpoint, the statistical analysis also includes pre-post comparisons with regard to the state of the patients before and after AP therapy. In addition, an analysis of the reasons that prevented physicians from implementing the antipsychotic deprescribing recommendation is performed, supplemented by a description of the patients with and without implementation of the recommendations by descriptive statistics.

—

Countries

Germany

Contacts

Public ContactJanine Diehl-Schmid

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Medizinische Fakultät der TU München

janine.diehl-schmid@tum.de089-41406488

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026