G93.2
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients: 1. patient is able to give informed consent and gives informed consent. 2. Signed informed consent. 3. Age from 18 to 70 years. 4. Diagnostic of idiopathic intracranial hypertension according to Friedman-criteria (Friedman et. al. 2013). 5. Planned lumbar puncture with measuring of the opening pressure. Inclusion criteria for healthy controls: 1. patient is able to give informed consent and gives informed consent. 2. Signed informed consent. 3. Age from 18 to 70 years. 4. no neurological or ophthalmological disease.
Exclusion criteria
Exclusion criteria: Exclusion criteria for patients: 1. non-corrected refractory anomalies >2,5 dpt res. 2,5 dpt res. <-2,5 dpt. 2. Other neuroophthalmological diseases influencing the pupillary light reflex.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Investigation of the pupillary light reflex in patients with idiopathic intracranial hypertension compared to healthy controls | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigation of the pupillary light reflex during the course of disease and in relation to clinical measures and findings in the clinical routine. Specifically the relation with the liquor opening pressure and with sonography of the orbita and the brain venes shall be investigated. In addition, quality of life and headache intensity will be measured longitudinally. | — |
Countries
Germany
Contacts
Klinik für NeurologieCharité – Universitätsmedizin BerlinCampus Virchow-Klinikum