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Pilot study on Idiopathic intracranial Hypertension: Evaluation of pupillometry as a clinical follow-up parameter

Pilot study on Idiopathic intracranial Hypertension: Evaluation of pupillometry as a clinical follow-up parameter

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00017815
Enrollment
50
Registered
2019-09-27
Start date
2019-10-13
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G93.2

Interventions

Group 1: In patients with IIH a pupillometry and testing of basic oculomotor abilities by video-oculography, sonography of the orbita and sonography of the venes supplying the brain and brain venes is

Sponsors

Charité Campus Virchow-KlinikumKlinik für Neurologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for patients: 1. patient is able to give informed consent and gives informed consent. 2. Signed informed consent. 3. Age from 18 to 70 years. 4. Diagnostic of idiopathic intracranial hypertension according to Friedman-criteria (Friedman et. al. 2013). 5. Planned lumbar puncture with measuring of the opening pressure. Inclusion criteria for healthy controls: 1. patient is able to give informed consent and gives informed consent. 2. Signed informed consent. 3. Age from 18 to 70 years. 4. no neurological or ophthalmological disease.

Exclusion criteria

Exclusion criteria: Exclusion criteria for patients: 1. non-corrected refractory anomalies >2,5 dpt res. 2,5 dpt res. <-2,5 dpt. 2. Other neuroophthalmological diseases influencing the pupillary light reflex.

Design outcomes

Primary

MeasureTime frame
Investigation of the pupillary light reflex in patients with idiopathic intracranial hypertension compared to healthy controls

Secondary

MeasureTime frame
Investigation of the pupillary light reflex during the course of disease and in relation to clinical measures and findings in the clinical routine. Specifically the relation with the liquor opening pressure and with sonography of the orbita and the brain venes shall be investigated. In addition, quality of life and headache intensity will be measured longitudinally.

Countries

Germany

Contacts

Public ContactPaula Haffner

Klinik für NeurologieCharité – Universitätsmedizin BerlinCampus Virchow-Klinikum

paula.haffner@charite.de+49 (30) 450 660 022

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026