Toxic fragments in post-mortem brain from SCA3 patients

Toxic fragments in post-mortem brain from SCA3 patients - cleave SCA3

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00017787

Enrollment

Registered

2019-11-26

Start date

2019-10-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinocerebellar Ataxia Type 3

Interventions

Group 1: SCA3 patients (post-mortem) Controls (post-mortem) Analysing potential toxic fragments in main pathogenesis area brain (post-mortem).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients are diagnosed as SCA3 post-mortem brain available controls did not died at a neurodegenerative disease

Exclusion criteria

Exclusion criteria: no consent given to use post-mortem brain for research

Design outcomes

Primary

Measure	Time frame
Detection of specific fragments in the brain yes/no	—

Secondary

Measure	Time frame
possible to use this as potential biomarker yes/no	—

Countries

Germany

Contacts

Public ContactJeannette Hübener-Schmid

Institut für Medizinische Genetik u. Angew. Genomik

jeannette.huebener@med.uni-tuebingen.de07071-2972276

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026