Barrier proteins and its regulation in inflammatory and non-inflammatory neuropathy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00017731

Enrollment

100

Registered

2019-07-30

Start date

2018-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G61.8 G62.9

Interventions

Group 1: Patients with inflammatory polyneuropathy: Examination of tissue sections of the sural nerve from biopsies taken for routine diagonals. Correlation with clinical phenotyping. Group 2: Patient

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Clinical criteria for polyneuropathy

Exclusion criteria

Exclusion criteria: Lack of information or consent of the patient; Pregnancy, other neurological disorders than polyneuropathy, ingestion of anticoagulants.

Design outcomes

Primary

Measure	Time frame
Altered expression of claudin-5	—

Secondary

Measure	Time frame
other tight junction proteins	—

Countries

Germany

Contacts

Public ContactHeike Rittner

Universitätsklinikum Würzburg - Zentrum für Interdisziplinäre SchmerzmedizinKlinik für Anästhesiologie

rittner_h@ukw.de0931 201 30251

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026