Neurocognitive effects in patients with advanced prostate cancer treated with androgen deprivation therapy

Neurocognitive effects in patients with advanced prostate cancer treated with androgen deprivation therapy - NEPPA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00017727

Enrollment

Registered

2019-08-05

Start date

2019-05-13

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C61

Interventions

Group 1: Patients with advanced prostate cancer will be assessed regarding their subjective perception of various psychological, psychosocial and cognitive domains. Moreover, the patients' cognitive f

Eligibility

Sex/Gender

Male

Age

45 Years to 85 Years

Inclusion criteria

Inclusion criteria: - Patients with advanced prostate cancer - Age: 45 - 85 years old - visiting the urooncological doctor's consultation at the National Center for Tumor Diseases Heidelberg and/or being treated on site - capacity to consent - signed informed consent

Exclusion criteria

Exclusion criteria: - Insufficiant knowledge of the German language - Neurological and/or psychiatric disorder - Incorrectable visual impairment

Design outcomes

Primary

Measure	Time frame
Cognitive Functioning The neurocognitive assessment includes four tests of the Wiener Testsystem (WTS), Schuhfried GmbH: - Wiener Wortflüssigkeitstest to measure lexical word fluency - Auditiver Wortlisten Lerntest to measure some aspects of the patients' memory and learning ability - Trail Making Test - Langensteinbacher Version to measure some aspects of executive functions - N-back verbal, another instrument to measure some aspects of executive functions Moreover, the subjective perception will be assessed using a questionnaire (Funcional Assessment of Cancer Therapy - Cognitive Function; FACT-Cog)	—

Measure

Time frame

Cognitive Functioning The neurocognitive assessment includes four tests of the Wiener Testsystem (WTS), Schuhfried GmbH: - Wiener Wortflüssigkeitstest to measure lexical word fluency - Auditiver Wortlisten Lerntest to measure some aspects of the patients' memory and learning ability - Trail Making Test - Langensteinbacher Version to measure some aspects of executive functions - N-back verbal, another instrument to measure some aspects of executive functions Moreover, the subjective perception will be assessed using a questionnaire (Funcional Assessment of Cancer Therapy - Cognitive Function; FACT-Cog)

—

Secondary

Measure	Time frame
Mental Health, measured with the Functional Assessment of Cancer Therapy - Prostate Cancer (FACT-P; questionnaire)	—

Countries

Germany

Contacts

Public ContactImad Maatouk

Universität Heidelberg, Psychoonkologische Ambulanz im NCT

Psychoonkologie@nct-heidelberg.de+49 6221 56-4727

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 10, 2026