Influence of the gastrointestinal microbiome on perioperative complications

Influence of the gastrointestinal microbiome on perioperative complications - GIMA-2 Trial (gastrointestinal microbiome analytic-2 Trial)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00017587

Enrollment

500

Registered

2019-08-13

Start date

2019-09-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41.9 T81.4

Interventions

Group 1: Analysis of the microbiome by Next Generation Sequencing of stool/plasma samples (preoperative, 5th day postoperative, if complications additional sample)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - major visceral surgery operation - a written declaration of consent by the study participant - Age >18 years

Exclusion criteria

Exclusion criteria: - Refusal to participate in the study - Chronic inflammatory bowel disease - pregnancy

Design outcomes

Primary

Measure	Time frame
Perioperative examination of changes in the gastrointestinal microbiome.	—

Secondary

Measure	Time frame
Investigation of changes in the microbiome in correlation with clinically relevant complications. Evaluation of the prognostic significance of microbial analysis.	—

Countries

Germany

Contacts

Public ContactFelix Schmitt

Universitätsklinikum Heidelberg Klinik für Anästhesiologie

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026