J96
Conditions
Interventions
Group 1: Mechanical ventilated patients who are ready for weaning will be followed up for 96 hours. During the spontaneous breathing trial (one hour) a measuring probe will be placed through a centra
Sponsors
Universitätsklinikum Augsburg, Abteilung für Anästhesiologie und Operative INtensivmedizin
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: patients with central venous line, patients ready for extubation, more than 48 hours on mechanical ventilation, no muscle rexaxants 24h bevore begin, hemoglobin >8g/dl, no clinical relevant acidosis, improvement of the reason the patient is ventilated for, temperature 90%, PaO2/FiO2 > 150; PEEP < 10 cm H2O; pressure support < 10 cm H2O
Exclusion criteria
Exclusion criteria: neurosurgical patients, patients under 18 and over 85 years, pregnancy, neuromuscular diseases, patients with tracheostoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Status of ventilation (extubated vs (re-)intubated) within 96 hours after measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-day-mortality 90-day-mortality Hospital mortality Days outside the intensive care unit (days which patients spent alive and outside of the ICU at day 28 after the spontaneous breathing trial) | — |
Countries
Germany
Contacts
Public ContactUlrich Jaschinski
Universitätsklinikum Augsburg, Abteilung für Anästhesiologie und Operative INtensivmedizin
Outcome results
None listed